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HomeProduct name listPHTHALAMIC ACID

PHTHALAMIC ACID

  • CAS NO.:88-97-1
  • Empirical Formula: C8H7NO3
  • Molecular Weight: 165.15
  • MDL number: MFCD00025476
  • EINECS: 201-871-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 17:34:43
PHTHALAMIC ACID Structural

What is PHTHALAMIC ACID?

The Uses of PHTHALAMIC ACID

Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.

The Uses of PHTHALAMIC ACID

Phthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite.

Definition

ChEBI: 2-carbamoylbenzoic acid is a carbamoylbenzoic acid.

General Description

Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide.

Properties of PHTHALAMIC ACID

Melting point: 140-143 °C(lit.)
Boiling point: 394.2±25.0 °C(Predicted)
Density  1.368
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 3.75±0.10(Predicted)
color  White to Off-White
BRN  1868205
CAS DataBase Reference 88-97-1(CAS DataBase Reference)
EPA Substance Registry System Benzoic acid, 2-(aminocarbonyl)- (88-97-1)

Safety information for PHTHALAMIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for PHTHALAMIC ACID

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