PHTHALAMIC ACID
- CAS NO.:88-97-1
- Empirical Formula: C8H7NO3
- Molecular Weight: 165.15
- MDL number: MFCD00025476
- EINECS: 201-871-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:43
What is PHTHALAMIC ACID?
The Uses of PHTHALAMIC ACID
Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.
The Uses of PHTHALAMIC ACID
Phthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite.
Definition
ChEBI: 2-carbamoylbenzoic acid is a carbamoylbenzoic acid.
General Description
Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide.
Properties of PHTHALAMIC ACID
Melting point: | 140-143 °C(lit.) |
Boiling point: | 394.2±25.0 °C(Predicted) |
Density | 1.368 |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 3.75±0.10(Predicted) |
color | White to Off-White |
BRN | 1868205 |
CAS DataBase Reference | 88-97-1(CAS DataBase Reference) |
EPA Substance Registry System | Benzoic acid, 2-(aminocarbonyl)- (88-97-1) |
Safety information for PHTHALAMIC ACID
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PHTHALAMIC ACID
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
AKOS BBS-00004780
PHTHALANILLIC ACID
2-[(4-chlorophenyl)carbamoyl]benzoic acid
2-([(4-IODOPHENYL)AMINO]CARBONYL)BENZOIC ACID
N-(4-(acetylsulphamoyl)phenyl)phthalamic acid
N-Metatolyl phthalamic acid
2-([(4-ETHYLPHENYL)AMINO]CARBONYL)BENZOIC ACID
TIMTEC-BB SBB007539
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