Phenyltrimethylammonium tribromide

Chemical properties

orange crystalline powder

The Uses of Phenyltrimethylammonium tribromide

Phenyltrimethylammonium tribromide is used as brominating reagent for 1,2-addition of bromine to the double bond of α,β-unsaturated compounds.

The Uses of Phenyltrimethylammonium tribromide

To the SM (340 mg, 2.7 mmol) in dry THF at RT was added Me3PhNBr3 (1.12 g, 3 mmol). The mixture was refluxed for 2 h, after which time it was quenched with H2O (2 x 20 mL) and extracted with EtOAc. The organic layer was dried (Na2SO4), concentrated, and purified by silica gel column chromatography (15% EtOAc/hexane) to provide the product. [100 mg]