PHENYLPROPIOLALDEHYDE DIETHYL ACETAL
Synonym(s):Phenylpropiolic aldehyde diethyl acetal
- CAS NO.:6142-95-6
- Empirical Formula: C13H16O2
- Molecular Weight: 204.26
- MDL number: MFCD00009238
- EINECS: 228-143-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-11-11 11:01:00
What is PHENYLPROPIOLALDEHYDE DIETHYL ACETAL?
Chemical properties
CLEAR COLOURLESS TO YELLOW LIQUID
Preparation
To a flask equipped with a 12-in. Vigreux column and distillation head is added 74.0 gm (0.50 mole) of triethyl orthoformate, 51.0 gm (0.50 mole)of phenylacetylene, and 3.0 gm of zinc iodide* catalyst. The flask must first be heated to 135°C before ethanol starts to reflux. The ethanol distillate (26.4 gm) boiling at 65°-88°C is removed over a period of 1 hr while the temperature of the reaction mixture is raised to 200°-210°C. The reaction mixture is cooled and filtered, the precipitate washed with 5 ml of ether and the ether combined with the filtrate is distilled to afford 73-80 gm (72-78%), b.p. 99-100°C (2.0 mm Hg). The IR spectrum showed absorption at 4.5-μ (—C=C—) and 9.0-μ region ( - C — O ).
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 2031, 1984 DOI: 10.1021/jo00185a045
Properties of PHENYLPROPIOLALDEHYDE DIETHYL ACETAL
Boiling point: | 99-100 °C2 mm Hg(lit.) |
Density | 0.991 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Sealed in dry,2-8°C |
BRN | 2049715 |
CAS DataBase Reference | 6142-95-6(CAS DataBase Reference) |
Safety information for PHENYLPROPIOLALDEHYDE DIETHYL ACETAL
Computed Descriptors for PHENYLPROPIOLALDEHYDE DIETHYL ACETAL
New Products
Tubulysin I Tubulysin H Tubulysin C 2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Potassium HMDS (1.0 M in THF) 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 3-N-BOC-(S)-AMINO BUTYRONITRILE 4,4-DIFLUOROPIPERIDINE 2,2-Difluoropropylamine hydrochloride 4,4-DIFLUOROCYCLOHEXANAMINE CYCLOBUTYLAMINE HYDROCHLORIDE (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateRelated products of tetrahydrofuran
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