PHENYLGLYOXAL MONOHYDRATE
Synonym(s):2,2-Dihydroxyacetophenone
- CAS NO.：1075-06-5
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00149499
- EINECS: 626-958-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is PHENYLGLYOXAL MONOHYDRATE?
The Uses of PHENYLGLYOXAL MONOHYDRATE
Phenylglyoxal monohydrate was used to modify pig muscle carbonic anhydraseIII and as a specific reagent for arginine groups. It was also used to prepare pyrrolinone and furan derivatives and as as a chemiluminescent reagent for the determination of purines.
What are the applications of Application
Phenylglyoxal is a potent inhibitor of mitochondrial ALDH (aldehyde dehydrogenase)
Biochem/physiol Actions
Phenylglyoxal is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.
Properties of PHENYLGLYOXAL MONOHYDRATE
| Melting point: | 76-79 °C(lit.) |
| Boiling point: | 142 °C125 mm Hg(lit.) |
| Density | 1.1603 (rough estimate) |
| refractive index | 1.5120 (estimate) |
| Flash point: | 142°C/125mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 95% ethanol: soluble5%, clear to very slightly hazy, colorless to light yellow |
| pka | 10.97±0.41(Predicted) |
| form | Powder |
| color | White to light yellow or pinkish |
| Water Solubility | Partly miscible with water. |
| BRN | 1854721 |
| CAS DataBase Reference | 1075-06-5(CAS DataBase Reference) |
Safety information for PHENYLGLYOXAL MONOHYDRATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PHENYLGLYOXAL MONOHYDRATE
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