H-Phe-Arg-βNA · 2 HCl

Synonym(s):PAβN

CAS NO.：100929-99-5
Empirical Formula: C25H32Cl2N6O2
Molecular Weight: 519.47
MDL number: MFCD00058046
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-16 21:30:20

What is H-Phe-Arg-βNA · 2 HCl?

Chemical properties

White powder

The Uses of H-Phe-Arg-βNA · 2 HCl

Substrate for dipeptidyl aminopeptidase I (cathepsin C).

The Uses of H-Phe-Arg-βNA · 2 HCl

Phe-Arg-beta-naphthylamide Dihydrochloride can be used as a reagent in organic synthesis.

The Uses of H-Phe-Arg-βNA · 2 HCl

Phe-Arg -naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.

General Description

Phe-Arg β-naphthylamide, a peptidomimetic compound, is an efflux pump inhibitor (EPI). It acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg -naphthylamide lowers fluoroquinolone resistance in Pseudomonas aeruginosa.

Properties of H-Phe-Arg-βNA · 2 HCl

Melting point:	>250o C
storage temp.	-20°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
Stability:	Hygroscopic

Safety information for H-Phe-Arg-βNA · 2 HCl

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H350:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P281:Use personal protective equipment as required. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..…