perlapine
- CAS NO.：1977-11-3
- Empirical Formula: C19H21N3
- Molecular Weight: 291.39
- MDL number: MFCD00867539
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is perlapine?
The Uses of perlapine
Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively). Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing. Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.
The Uses of perlapine
Perlapine exhibits antipsychotic activity and blocks dopamine and serotonin receptors. Perlapine is also a novel agonist of hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD).
Definition
ChEBI: Perlapine is an organic molecular entity.
storage
Room temperature
Properties of perlapine
| Melting point: | 136-138° |
| Boiling point: | 423.4°C (rough estimate) |
| Density | 1.0521 (rough estimate) |
| refractive index | 1.6080 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| pka | 8.00±0.20(Predicted) |
| color | White |
Safety information for perlapine
Computed Descriptors for perlapine
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