Pentafluorobenzoyl chloride
Synonym(s):Pentafluorobenzoic acid chloride;Perfluorobenzoyl chloride
- CAS NO.:2251-50-5
- Empirical Formula: C7ClF5O
- Molecular Weight: 230.52
- MDL number: MFCD00000657
- EINECS: 218-842-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-22 16:43:48
What is Pentafluorobenzoyl chloride?
Description
Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.
2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.
Chemical properties
clear colorless to light yellow liquid
The Uses of Pentafluorobenzoyl chloride
Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.
The Uses of Pentafluorobenzoyl chloride
Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.
The Uses of Pentafluorobenzoyl chloride
A reagent used for deriving primary amines. 2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivative dimethylamine(DMA) in study to develop a rapid and accurate GC-MS method for determination of DMA in human urine. It was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.
What are the applications of Application
2,3,4,5,6-Pentafluorobenzoyl chloride is a reagent used for deriving primary amines
Definition
ChEBI: The acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography.
Properties of Pentafluorobenzoyl chloride
Boiling point: | 158-159 °C(lit.) |
Density | 1.601 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | None |
storage temp. | Store below +30°C. |
solubility | soluble in Chloroform |
form | Liquid |
Specific Gravity | 1.601 |
color | Clear colorless to light yellow |
Water Solubility | decomposes |
Sensitive | Lachrymatory |
BRN | 2054397 |
Stability: | Moisture Sensitive |
CAS DataBase Reference | 2251-50-5(CAS DataBase Reference) |
NIST Chemistry Reference | Pentafluorobenzoyl chloride(2251-50-5) |
Safety information for Pentafluorobenzoyl chloride
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Pentafluorobenzoyl chloride
InChIKey | MYHOHFDYWMPGJY-UHFFFAOYSA-N |
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