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HomeProduct name listPENTAFLUOROBENZENESULFONYL FLUORESCEIN

PENTAFLUOROBENZENESULFONYL FLUORESCEIN

PENTAFLUOROBENZENESULFONYL FLUORESCEIN Structural

What is PENTAFLUOROBENZENESULFONYL FLUORESCEIN?

Description

Reactive oxygen species (ROS) play important roles in the initiation and progression of many disease processes. Most fluorescent probes for ROS detection, such as 2,7-dichlorofluorescein (DCFH), function by an oxidative mechanism and are useful for total oxidant detection but are not selective for hydrogen peroxide specifically.1 Pentafluorobenzenesulfonyl fluorescein is a fluorescent probe that functions by a nonoxidative mechanism. It fluoresces upon perhydrolysis of the sulfonyl linkage, and is selective for hydrogen peroxide over hydroxyl radical, tert-butyl hydroperoxide, superoxide anion, singlet oxygen, and nitrates. Pentafluorobenzenesulfonyl fluorescein can be used as a probe for hydrogen peroxide in whole cell systems.1

What are the applications of Application

Pentafluorobenzenesulfonyl fluorescein is a fluorescent probe that functions by a nonoxidative mechanism

References

1. Maeda, H., Fukuyasu, Y., Yoshida, S., et al. Fluorescent probes for hydrogen peroxide based on a non-oxidative mechanism Angew. Chem. Int. Ed. Engl. 43(18),2389-2391(2004).

Properties of PENTAFLUOROBENZENESULFONYL FLUORESCEIN

storage temp.  Store at -20°C
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .25 mg/ml; Ethanol: 20 mg/ml
form  A crystalline solid

Safety information for PENTAFLUOROBENZENESULFONYL FLUORESCEIN

Computed Descriptors for PENTAFLUOROBENZENESULFONYL FLUORESCEIN

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