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HomeProduct name listPD 135158

PD 135158

PD 135158 Structural

What is PD 135158?

What are the applications of Application

PD 135158 is a selective CCK-BR antagonist used for research purposes

Biological Activity

Potent and selective, nonpeptide CCK 2 receptor antagonist (IC 50 values are 2.8 and 1232 nM for CCK 2 and CCK 1 respectively) that displays negligible affinity at GABA A , benzodiazepine, substance P, neurotensin, opioid, bradykinin and 5-HT 3 receptors (IC 50 > 10 μ M). Exhibits anxiolytic activity in elevated plus maze and social interaction tests and increases food intake in rats.

Properties of PD 135158

storage temp.  Store at +4°C
solubility  <61.68mg/ml in DMSO

Safety information for PD 135158

Computed Descriptors for PD 135158

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