PD 135158
- CAS NO.：130325-35-8
- Empirical Formula: C42H61N5O11
- Molecular Weight: 811.97
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:03
What is PD 135158?
What are the applications of Application
PD 135158 is a selective CCK-BR antagonist used for research purposes
Biological Activity
Potent and selective, nonpeptide CCK 2 receptor antagonist (IC 50 values are 2.8 and 1232 nM for CCK 2 and CCK 1 respectively) that displays negligible affinity at GABA A , benzodiazepine, substance P, neurotensin, opioid, bradykinin and 5-HT 3 receptors (IC 50 > 10 μ M). Exhibits anxiolytic activity in elevated plus maze and social interaction tests and increases food intake in rats.
Properties of PD 135158
| storage temp. | Store at +4°C |
| solubility | <61.68mg/ml in DMSO |
Safety information for PD 135158
Computed Descriptors for PD 135158
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