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HomeProduct name listParbendazole

Parbendazole

Synonym(s):Methyl (5-butyl-1H-benzoimidazol-2-yl)carbamate;Methyl 5(6)-butyl-2-benzimidazolecarbamate

  • CAS NO.:14255-87-9
  • Empirical Formula: C13H17N3O2
  • Molecular Weight: 247.29
  • MDL number: MFCD00864534
  • EINECS: 238-133-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-02 19:02:54
Parbendazole Structural

What is Parbendazole?

Chemical properties

solid

The Uses of Parbendazole

Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.

The Uses of Parbendazole

Antiparasitic

Definition

ChEBI: N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester is a carbamate ester and a member of benzimidazoles.

General Description

Crystals or fine white powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.

Fire Hazard

Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.

Properties of Parbendazole

Melting point: 255-257°C
Boiling point: 390.33°C (rough estimate)
Density  1.1214 (rough estimate)
refractive index  1.5700 (estimate)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form  neat
pka 11.66±0.10(Predicted)
form  Solid
color  White to Off-White
Water Solubility  <0.1 g/100 mL at 18 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System Parbendazole (14255-87-9)

Safety information for Parbendazole

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H302:Acute toxicity,oral
H361:Reproductive toxicity
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Parbendazole

InChIKey YRWLZFXJFBZBEY-UHFFFAOYSA-N

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