Parbendazole
Synonym(s):Methyl (5-butyl-1H-benzoimidazol-2-yl)carbamate;Methyl 5(6)-butyl-2-benzimidazolecarbamate
- CAS NO.：14255-87-9
- Empirical Formula: C13H17N3O2
- Molecular Weight: 247.29
- MDL number: MFCD00864534
- EINECS: 238-133-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is Parbendazole?
Chemical properties
solid
The Uses of Parbendazole
Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.
The Uses of Parbendazole
Antiparasitic
Definition
ChEBI: N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester is a carbamate ester and a member of benzimidazoles.
General Description
Crystals or fine white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.
Fire Hazard
Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.
Properties of Parbendazole
| Melting point: | 255-257°C |
| Boiling point: | 390.33°C (rough estimate) |
| Density | 1.1214 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| form | neat |
| pka | 11.66±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | <0.1 g/100 mL at 18 ºC |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| EPA Substance Registry System | Parbendazole (14255-87-9) |
Safety information for Parbendazole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H361:Reproductive toxicity |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Parbendazole
| InChIKey | YRWLZFXJFBZBEY-UHFFFAOYSA-N |
Parbendazole manufacturer
Molsyns Research
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