Palmitoyl chloride

Synonym(s):Hexadecanoyl chloride;Palmitoyl chloride

CAS NO.：112-67-4
Empirical Formula: C16H31ClO
Molecular Weight: 274.87
MDL number: MFCD00000742
EINECS: 203-996-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-08-04 21:29:34

What is Palmitoyl chloride?

Chemical properties

clear liquid

The Uses of Palmitoyl chloride

Palmitoyl Chloride was used as a polymeric carriers for plasmid DNA (pDNA) delivery to 293T cells.

The Uses of Palmitoyl chloride

Palmitoyl chloride is a compound which has been used as a polymeric carrier for plasmid DNA delivery to 293T cells.

What are the applications of Application

Palmitoyl chloride is a compound which has been used as a polymeric carrier for plasmid DNA delivery to 293T cells

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 6101, 1989 DOI: 10.1021/jo00287a023

General Description

A clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12°C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.

Air & Water Reactions

Decomposes rather slowly in water to form hydrochloric acid and palmitic acid, a fatty acid that is not soluble in water.

Reactivity Profile

HEXADECANOYL CHLORIDE is incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Flammability and Explosibility

Not classified

Properties of Palmitoyl chloride

Melting point:	11-13 °C (lit.)
Boiling point:	88-90 °C/0.2 mmHg (lit.)
Density	0.906 g/mL at 25 °C (lit.)
refractive index	n20/D 1.452(lit.)
Flash point:	>230 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly)
form	Liquid
color	Clear
Specific Gravity	0.905
Water Solubility	Decomposition
Sensitive	Moisture Sensitive
BRN	972409
Stability:	Moisture Sensitive
CAS DataBase Reference	112-67-4(CAS DataBase Reference)
NIST Chemistry Reference	Palmitoyl chloride(112-67-4)
EPA Substance Registry System	Hexadecanoyl chloride (112-67-4)

Safety information for Palmitoyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.