PALMITOYL CARNITINE
Synonym(s):(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium inner salt;L -Carnitine hexadecanoyl ester;C16-Carnitine;Hexadecanoyl-L -carnitine
- CAS NO.：2364-67-2
- Empirical Formula: C23H45NO4
- Molecular Weight: 0
- MDL number: MFCD00152152
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:21
What is PALMITOYL CARNITINE?
The Uses of PALMITOYL CARNITINE
L-?Palmitoyl Carnitine is used as a diagnostic agent in the investigation of drug toxicity with respect to the liver. Acts as a biomarker in the study of metabolism in metabolic diseases.
Definition
ChEBI: An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl).
General Description
Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts.
Biochem/physiol Actions
L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics.
Properties of PALMITOYL CARNITINE
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| optical activity | [α]/D -17±2°, c = 1 in methanol |
| BRN | 4152034 |
Safety information for PALMITOYL CARNITINE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for PALMITOYL CARNITINE
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