P-TOLUENESULFONYL FLUORIDE
- CAS NO.:455-16-3
- Empirical Formula: C7H7FO2S
- Molecular Weight: 174.19
- MDL number: MFCD00007421
- EINECS: 207-238-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is P-TOLUENESULFONYL FLUORIDE?
Chemical properties
White to beige fused mass
The Uses of P-TOLUENESULFONYL FLUORIDE
p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
The Uses of P-TOLUENESULFONYL FLUORIDE
Protease inhibitor.
General Description
p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.
Properties of P-TOLUENESULFONYL FLUORIDE
Melting point: | 41-42 °C(lit.) |
Boiling point: | 112 °C16 mm Hg(lit.) |
Density | 1.2768 (estimate) |
Flash point: | 222 °F |
Water Solubility | Hydrolyzes in water. |
Sensitive | Moisture Sensitive |
BRN | 2208423 |
Exposure limits | ACGIH: TWA 2.5 mg/m3 NIOSH: IDLH 250 mg/m3 |
CAS DataBase Reference | 455-16-3(CAS DataBase Reference) |
EPA Substance Registry System | Benzenesulfonyl fluoride, 4-methyl- (455-16-3) |
Safety information for P-TOLUENESULFONYL FLUORIDE
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for P-TOLUENESULFONYL FLUORIDE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
P-TOLUENESULFINIC ACID
p-Toluenesulfonic acid
p-Toluenesulfonic acid monohydrate
toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester
4-(FLUOROSULFONYL)BENZOIC ACID
SULFORHODAMINE B 5-ACID FLUORIDE
4-(CHLOROMETHYL)BENZENESULPHONYL FLUORIDE
8-CYCLOPENTYL-N3-[3-(4-(FLUOROSULFONYL)BENZOYLOXY)PROPYL]-N1-PROPYLXANTHINE
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