P-TOLUENESULFONYL FLUORIDE

CAS NO.：455-16-3
Empirical Formula: C7H7FO2S
Molecular Weight: 174.19
MDL number: MFCD00007421
EINECS: 207-238-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is P-TOLUENESULFONYL FLUORIDE?

Chemical properties

White to beige fused mass

The Uses of P-TOLUENESULFONYL FLUORIDE

p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.

The Uses of P-TOLUENESULFONYL FLUORIDE

Protease inhibitor.

General Description

p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.

Properties of P-TOLUENESULFONYL FLUORIDE

Melting point:	41-42 °C(lit.)
Boiling point:	112 °C16 mm Hg(lit.)
Density	1.2768 (estimate)
Flash point:	222 °F
Water Solubility	Hydrolyzes in water.
Sensitive	Moisture Sensitive
BRN	2208423
Exposure limits	ACGIH: TWA 2.5 mg/m3 NIOSH: IDLH 250 mg/m3
CAS DataBase Reference	455-16-3(CAS DataBase Reference)
EPA Substance Registry System	Benzenesulfonyl fluoride, 4-methyl- (455-16-3)

Safety information for P-TOLUENESULFONYL FLUORIDE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.