p-Acetylamino benzoic acid

Chemical properties

white or off-white powder or crystals

Originator

4-Acetamidobenzoic acid ,ARIAC

The Uses of p-Acetylamino benzoic acid

immune stimulant (component)

The Uses of p-Acetylamino benzoic acid

Acedoben is the acetylated derivative of p-aminobenzoic acid (PABA). Acedoben is a metabolite of the anesthetic Benzocaine (B202970).

What are the applications of Application

4-Acetamidobenzoic Acid is an acetylated derivative of p-aminobenzoic acid (PABA)

Definition

ChEBI: A amidobenzoic acid that consists of benzoic acid bearing an acetamido substituent at position 4.

Manufacturing Process

Into a 2 L, 3-necked flask set in a tub and equipped with a stirrer, an air condenser (drying tube), thermometer, was placed 860 ml of water, 43.0 g of MgSO4 and 43.0 g of sodium acetate and heated on water bath. Into heated solution to 70°C stirring 43.0 g of N-p-tolylacetamide were added. Then 136.0 g of KMnO4 by small portions were added at 75°-80°C. The reaction mixture allow to stand for 6 h and stirring was continue till the solution became colorless. Hot solution was filtered and filtrate treated hydrochloric acid to slightly acidic pH. After that 44.0 g (85%) of p-acetoaminobenzoic acid was obtained as white precipitate, melting point 250°C.

Therapeutic Function

Antiviral

General Description

Needles or off-white powder.

Air & Water Reactions

Water insoluble.

Reactivity Profile

Simultaneously an amide and a carboxylic acid.

Fire Hazard

Flash point data for p-Acetylamino benzoic acid are not available; however, p-Acetylamino benzoic acid is probably combustible.