Oxyphenonium bromide
- CAS NO.:50-10-2
- Empirical Formula: C21H34BrNO3
- Molecular Weight: 428.4
- MDL number: MFCD00050259
- EINECS: 200-010-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:54
What is Oxyphenonium bromide?
Originator
A-Spasm ,Acme Laboratories Ltd.
The Uses of Oxyphenonium bromide
anticholinergic, anticonvulsant
What are the applications of Application
Oxyphenonium bromide is a quaternary ammonium antimuscarinic and anticholinergic agent
Manufacturing Process
1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.
brand name
Antrenyl (Novartis).
Therapeutic Function
Anticholinergic, Spasmolytic
Safety Profile
Poison by ingestion, intramuscular, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: change in heart rate. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Brí.
Properties of Oxyphenonium bromide
Melting point: | 189-194° from ethyl acetate + alc |
Density | 1.2584 (rough estimate) |
refractive index | 1.6200 (estimate) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | A solid |
color | White to Off-White |
Safety information for Oxyphenonium bromide
Computed Descriptors for Oxyphenonium bromide
Abamectin manufacturer
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