oxycinchophen

CAS NO.：485-89-2
Empirical Formula: C16H11NO3
Molecular Weight: 265.26
MDL number: MFCD00023966
EINECS: 2076244
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is oxycinchophen?

The Uses of oxycinchophen

Oxicinchophen has bene used to study P-selectin antagonistic activity, DHOD inhibitory activity, SAR of quinoline salicylic acids using Pfitzinger reaction of isatin derivatives with (acetyloxy)acetophenone derivatives; effect of antiinflammatory drugs on vascular smooth muscle; increase in oxygen consumption in the absence of a phosphate acceptor and to inhibit ATP synthesis in the isolated rat liver mitochondria.

Definition

ChEBI: Oxycinchophen is a member of quinolines.

Safety Profile

Low toxicity by ingestion and skin contact. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

It is precipitated from alkaline solution on acidification and crystallises from EtOH or AcOH in yellow crystals. [Marshall & Blanchard J Pharmacol 95 186 1949, Beilstein 22 H 245, 22 II 183, 22 III/IV 2383.]

Properties of oxycinchophen

Melting point:	206.5°C (rough estimate)
Boiling point:	408.48°C (rough estimate)
Density	1.1861 (rough estimate)
refractive index	1.5300 (estimate)
storage temp.	2-8°C
pka	0.55±0.10(Predicted)
color	Minute, deep yellow prisms from alc

Safety information for oxycinchophen

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.