Epothilone C
- CAS NO.：186692-73-9
- Empirical Formula: C26H39NO5S
- Molecular Weight: 477.66
- MDL number: MFCD02102104
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 09:33:14
What is Epothilone C?
The Uses of Epothilone C
Epothilone C is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
Definition
ChEBI: Epothilone C is an epothilone that is 1-oxacyclohexadec-13-ene-2,6-dione which is substituted by hydroxy groups at positions 4 and 9, methyl groups at positions 5, 5, 7, and 9, and by a (1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl group at position 16 (the 4S,7R,8S,9S,13Z,16S stereoisomer).
Properties of Epothilone C
| Boiling point: | 657.7±55.0 °C(Predicted) |
| Density | 1.097 |
| pka | 13.47±0.70(Predicted) |
Safety information for Epothilone C
Computed Descriptors for Epothilone C
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