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HomeProduct name listO-PHOSPHO-L-THREONINE

O-PHOSPHO-L-THREONINE

Synonym(s):(S)-2-Amino-3-hydroxybutanoic acid 3-phosphate;L-Threonine O-phosphate

  • CAS NO.:1114-81-4
  • Empirical Formula: C4H10NO6P
  • Molecular Weight: 199.1
  • MDL number: MFCD00069578
  • EINECS: 214-217-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-14 20:44:35
O-PHOSPHO-L-THREONINE Structural

What is O-PHOSPHO-L-THREONINE?

Definition

ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).

Biochem/physiol Actions

O-Phospho-L-threonine is an amino acid derivative.

Purification Methods

Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]

Properties of O-PHOSPHO-L-THREONINE

Melting point: 169 °C
Boiling point: 454.0±55.0 °C(Predicted)
Density  1.671±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  NH4OH 1 M: 0.1 g/mL, clear, colorless
pka 1.73±0.10(Predicted)
form  A solid
BRN  1727078

Safety information for O-PHOSPHO-L-THREONINE

Computed Descriptors for O-PHOSPHO-L-THREONINE

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