O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Synonym(s):O-(4-·Hydroxyphenyl)-3-,3′-·diiodo-L-tyrosine;3,3′-·Diiodo-·4-·(4-·hydroxyphenoxy)·-L-phenylalanine;T2

CAS NO.：4604-41-5
Empirical Formula: C15H13I2NO4
Molecular Weight: 525.08
MDL number: MFCD01863378
EINECS: 225-005-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Structural

What is O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine?

Description

3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.

Chemical properties

Off-White Powder

The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus

The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.

Definition

ChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite.

Properties of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Melting point:	178-180°C
Boiling point:	520.7±50.0 °C(Predicted)
Density	2.095±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Aqueous Base (Slightly)
form	Solid
pka	2.17±0.20(Predicted)
color	Off-White to Beige
Stability:	Light Sensitive

Safety information for O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.