O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Synonym(s):O-(4-·Hydroxyphenyl)-3-,3′-·diiodo-L -tyrosine;3,3′-·Diiodo-·4-·(4-·hydroxyphenoxy)·-L -phenylalanine;T2
- CAS NO.：4604-41-5
- Empirical Formula: C15H13I2NO4
- Molecular Weight: 525.08
- MDL number: MFCD01863378
- EINECS: 225-005-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine?
Description
3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.
Chemical properties
Off-White Powder
The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus
The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.
Definition
ChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite.
Properties of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
| Melting point: | 178-180°C |
| Boiling point: | 520.7±50.0 °C(Predicted) |
| Density | 2.095±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Aqueous Base (Slightly) |
| form | Solid |
| pka | 2.17±0.20(Predicted) |
| color | Off-White to Beige |
| Stability: | Light Sensitive |
Safety information for O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
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product: LEVOTHYROXINE EP IMPURITY J | 3,3-DIIODO-L-THYRONINE 97.94
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