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HomeProduct name listO-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Synonym(s):O-(4-·Hydroxyphenyl)-3-,3′-·diiodo-L-tyrosine;3,3′-·Diiodo-·4-·(4-·hydroxyphenoxy)·-L-phenylalanine;T2

  • CAS NO.:4604-41-5
  • Empirical Formula: C15H13I2NO4
  • Molecular Weight: 525.08
  • MDL number: MFCD01863378
  • EINECS: 225-005-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Structural

What is O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine?

Description

3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.

Chemical properties

Off-White Powder

The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus

The Uses of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.

Definition

ChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite.

Properties of O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Melting point: 178-180°C
Boiling point: 520.7±50.0 °C(Predicted)
Density  2.095±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  Aqueous Base (Slightly)
form  Solid
pka 2.17±0.20(Predicted)
color  Off-White to Beige
Stability: Light Sensitive

Safety information for O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

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