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HomeProduct name listNYLIDRIN HYDROCHLORIDE

NYLIDRIN HYDROCHLORIDE

  • CAS NO.:849-55-8
  • Empirical Formula: C19H26ClNO2
  • Molecular Weight: 335.87
  • MDL number: MFCD00035085
  • EINECS: 212-701-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-01 13:17:44
NYLIDRIN HYDROCHLORIDE Structural

What is NYLIDRIN HYDROCHLORIDE?

Chemical properties

White, crystals or powder, odorless; tasteless. Slightly soluble in water and alcohol; very slightly soluble in chloroform, ether; pH of 1% solution is between 4.5 and 6.5.

Originator

Buphenine hydrochloride,Troponwerke

The Uses of NYLIDRIN HYDROCHLORIDE

Medicine (treatment of heart disease).

Definition

ChEBI: Nylidrin hydrochloride is an alkylbenzene.

Manufacturing Process

The p-benzoxy-α-bromopropiophenone and 1-phenyl-3-amino-butane were heating for an hour on the water bath in the absence of solvents. A solid crystalline cake was obtained. After being extracted with boiling acetic acid, the hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-1 was obtained.
The hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone- 1 was suspended in very pure methanol and shaken with a 10% palladium hydroxide barium sulfate catalyst in contact with, hydrogen. After rather more than 2 mols of hydrogen had been taken-up the hydrogenation stopped. The 1-(p-hydroxyphenyl)-2-(3-phenylbutylamino)propanol-1, was filtered, washed with methanol and evaporated, melting point 110-111°C.

Therapeutic Function

Vasodilator

Properties of NYLIDRIN HYDROCHLORIDE

Melting point: 198-199℃ (decomposition)
storage temp.  Store at -20°C
solubility  DMSO: ≥ 41 mg/mL (122.07 mM)
form  Solid
color  White to Off-White

Safety information for NYLIDRIN HYDROCHLORIDE

Computed Descriptors for NYLIDRIN HYDROCHLORIDE

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