NYLIDRIN HYDROCHLORIDE
- CAS NO.:849-55-8
- Empirical Formula: C19H26ClNO2
- Molecular Weight: 335.87
- MDL number: MFCD00035085
- EINECS: 212-701-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 13:17:44
What is NYLIDRIN HYDROCHLORIDE?
Chemical properties
White, crystals or powder, odorless; tasteless. Slightly soluble in water and alcohol; very slightly soluble in chloroform, ether; pH of 1% solution is between 4.5 and 6.5.
Originator
Buphenine hydrochloride,Troponwerke
The Uses of NYLIDRIN HYDROCHLORIDE
Medicine (treatment of heart disease).
Definition
ChEBI: Nylidrin hydrochloride is an alkylbenzene.
Manufacturing Process
The p-benzoxy-α-bromopropiophenone and 1-phenyl-3-amino-butane were
heating for an hour on the water bath in the absence of solvents. A solid
crystalline cake was obtained. After being extracted with boiling acetic acid,
the hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-1
was obtained.
The hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-
1 was suspended in very pure methanol and shaken with a 10% palladium
hydroxide barium sulfate catalyst in contact with, hydrogen. After rather more
than 2 mols of hydrogen had been taken-up the hydrogenation stopped. The
1-(p-hydroxyphenyl)-2-(3-phenylbutylamino)propanol-1, was filtered, washed
with methanol and evaporated, melting point 110-111°C.
Therapeutic Function
Vasodilator
Properties of NYLIDRIN HYDROCHLORIDE
Melting point: | 198-199℃ (decomposition) |
storage temp. | Store at -20°C |
solubility | DMSO: ≥ 41 mg/mL (122.07 mM) |
form | Solid |
color | White to Off-White |
Safety information for NYLIDRIN HYDROCHLORIDE
Computed Descriptors for NYLIDRIN HYDROCHLORIDE
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