NSC 625987
Synonym(s):1,4-Dimethoxyacridine-9(10H)-thione;Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem
- CAS NO.：141992-47-4
- Empirical Formula: C15H13NO2S
- Molecular Weight: 271.33
- MDL number: MFCD08276925
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is NSC 625987?
The Uses of NSC 625987
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.
What are the applications of Application
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor
Definition
ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.
Biological Activity
Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
Properties of NSC 625987
| storage temp. | 2-8°C |
| solubility | DMSO: 14 mg/mL |
| form | Powder |
| color | Brown to khaki |
Safety information for NSC 625987
Computed Descriptors for NSC 625987
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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