NORCODEINE
- CAS NO.：467-15-2
- Empirical Formula: C17H19NO3
- Molecular Weight: 285.34
- MDL number: MFCD00069317
- EINECS: 207-388-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:54
What is NORCODEINE?
Chemical properties
Crystalline Solid
The Uses of NORCODEINE
(-)-N-Norcodeine is a metabolite of Codeine. Morphine derivative.
Definition
ChEBI: A morphinane-like compound that is the N-demethylated derivative of codeine.
Purification Methods
It crystallises from acetone or ethyl acetate. [Speyer & Walther Chem Ber 63 822 1930.] The hydrochloride has m 309o(dec) when crystallised from H2O. [Beilstein 18 III/IV 8091.]
Properties of NORCODEINE
| Melting point: | 1850C |
| Boiling point: | 467.7±45.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| Flash point: | 9℃ |
| storage temp. | -20°C |
| solubility | DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | pKa 9.23± 0.01(H2O,t =25±0.1,I=0.15(KCl)Ar)(Approximate) |
Safety information for NORCODEINE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for NORCODEINE
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