N,N-Dimethyltrimethylsilylamine

Synonym(s):(Dimethylamino)trimethylsilane;N-(Trimethylsilyl)dimethylamine;TMSDMA

CAS NO.：2083-91-2
Empirical Formula: C5H15NSi
Molecular Weight: 117.26
MDL number: MFCD00008297
EINECS: 218-222-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

N,N-Dimethyltrimethylsilylamine Structural

What is N,N-Dimethyltrimethylsilylamine?

Chemical properties

clear colorless to pale yellow liquid

The Uses of N,N-Dimethyltrimethylsilylamine

N,N-Dimethyltrimethylsilylamine was used in the synthesis of phosphoramidite. It was also employed as a reagent in the preparation of iminium salts and amides as well as for the silylation of polymers. A combination of N-(trimethylsilyl)dimethylamine and MeI was also effective to give p-methylbenzoic acid with a 85% yield based on 90% conversion from the corresponding Me ester. DETA has been treated with N-(trimethylsilyl)-dimethylamine to yield mono-, di- and tri- silylated derivatives

Properties of N,N-Dimethyltrimethylsilylamine

Melting point:	<0°C
Boiling point:	84 °C (lit.)
Density	0.732 g/mL at 25 °C (lit.)
refractive index	n20/D 1.397(lit.)
Flash point:	−3 °F
storage temp.	Flammables area
form	clear liquid
pka	10.77±0.70(Predicted)
Specific Gravity	0.74
color	Colorless to Light yellow
Water Solubility	Decomposition
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	1731861
CAS DataBase Reference	2083-91-2(CAS DataBase Reference)
NIST Chemistry Reference	Dimethylamino(trimethyl)silane(2083-91-2)
EPA Substance Registry System	Silanamine, pentamethyl- (2083-91-2)

Safety information for N,N-Dimethyltrimethylsilylamine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05
GHS Hazard Statements	H225:Flammable liquids H260:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases H314:Skin corrosion/irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P223:Keep away from any possible contact with water, because of violent reaction and possible flash fire. P280:Wear protective gloves/protective clothing/eye protection/face protection. P231+P232:Handle under inert gas. Protect from moisture. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.