Nitrapyrin

Synonym(s):2-Chloro-6-(trichloromethyl)pyridine;CP;Nitrapyrin

CAS NO.：1929-82-4
Empirical Formula: C6H3Cl4N
Molecular Weight: 230.91
MDL number: MFCD00072500
EINECS: 217-682-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-13 19:17:58

What is Nitrapyrin?

Chemical properties

Crystals.

Physical properties

Colorless to white crystalline solid with a mild, sweet odor

The Uses of Nitrapyrin

2-Chloro-6-(trichloromethyl)pyridine is

The Uses of Nitrapyrin

Bactericide used to inhibit Nitrosomonas spp. from oxidizing ammonium ions in soil.

The Uses of Nitrapyrin

Fertilizer additive to control nitrification and prevent loss of soil nitrogen.

Definition

ChEBI: Nitrapyrin is a chloropyridine that is 2-chloropyridine which is substituted by a trichloromethyl group at position 6. It is a nitrification inhibitor that is co-applied with nitrogen fertilizer in agroecosystems. It has a role as a nitrification inhibitor, an antibacterial agent and an agrochemical.

General Description

Colorless crystals or off-white crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Nitrapyrin is a base. Reacts exothermically with acids.

Hazard

Liver damage. Questionable carcinogen.

Fire Hazard

Flash point data for Nitrapyrin are not available. Nitrapyrin is probably combustible.

Flammability and Explosibility

Non flammable

Agricultural Uses

Nitrapyrin, also called N serve, is a nitrification inhibitor

Safety Profile

Poison by ingestion. Moderately toxic by skin contact. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.

Environmental Fate

Biological. 6-Chloropicolinic acid and carbon dioxide were reported as biodegradation products (Verschueren, 1983).
Soil. Hydrolyzes in soil to 6-chloropyridine-2-carboxylic acid (Worthing and Hance, 1991).
Photolytic. Photolysis of nitrapyrin in water yielded 6-chloropicolinic acid, 6-hydroxypicolinic acid and an unidentified polar material (Verschueren, 1983).
Chemical/Physical. Emits toxic fumes of nitrogen oxides and chlorides when heated to decomposition (Sax and Lewis, 1987; Lewis, 1990).

Properties of Nitrapyrin

Melting point:	62-63°C
Boiling point:	136-138°C
Density	1.8732 (rough estimate)
vapor pressure	2.8 x 10^-3 mmHg at 20 °C (quoted, Verschueren, 1983)
refractive index	1.6000 (estimate)
Flash point:	100 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in 10 mg/ml ethanol.
form	Powder
pka	-3.75±0.10(Predicted)
Specific Gravity	1.579 (25℃)
color	White
Water Solubility	Insoluble. <0.01 g/100 mL at 18 ºC
Merck	14,6574
BRN	1618997
Henry's Law Constant	2.13 x 10^-3 atm?m³/mol (approximate - calculated from water solubility and vapor pressure)
Exposure limits	NIOSH REL: 10 mg/m3, STEL 20 mg/m3 (total), 5 mg/m3 (respirable fraction); OSHA PEL: 15 mg/m3 (total), 5 mg/m3 (respirable fraction); ACGIH TLV: TWA 10 mg/m3.
CAS DataBase Reference	1929-82-4(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2-chloro-6-(trichloromethyl)-(1929-82-4)
EPA Substance Registry System	Nitrapyrin (1929-82-4)

Safety information for Nitrapyrin

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H311:Acute toxicity,dermal H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.