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HomeProduct name listNEUROTENSIN (8-13)

NEUROTENSIN (8-13)

NEUROTENSIN (8-13) Structural

What is NEUROTENSIN (8-13)?

Biological Activity

Neurotensin (8-13) is the active fragment of neurotensin, Neurotensin (8-13) reduces cell surface NT1 receptor (NTR1) density.

in vitro

Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT ) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.

Properties of NEUROTENSIN (8-13)

Density  1.40±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C
form  Solid
pka 3.41±0.10(Predicted)
color  White to off-white
Water Solubility  Water: 50 mg/mL (61.20 mM)

Safety information for NEUROTENSIN (8-13)

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for NEUROTENSIN (8-13)

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