NEUROTENSIN (8-13)
- CAS NO.：60482-95-3
- Empirical Formula: C38H64N12O8
- Molecular Weight: 816.99
- MDL number: MFCD00076686
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:58
What is NEUROTENSIN (8-13)?
Biological Activity
Neurotensin (8-13) is the active fragment of neurotensin, Neurotensin (8-13) reduces cell surface NT1 receptor (NTR1) density.
in vitro
Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT ) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.
Properties of NEUROTENSIN (8-13)
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| form | Solid |
| pka | 3.41±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Water: 50 mg/mL (61.20 mM) |
Safety information for NEUROTENSIN (8-13)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for NEUROTENSIN (8-13)
New Products
Tubulysin G Tubulysin I (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 2H-Pyran, 4-ethynyltetrahydro- 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3,3-Difluoropyrrolidine 1-(1,1-Difluoroethyl)-2-fluorobenzene (S)-3-Aminobutanenitrile hydrochloride ? 4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide ? (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 3-Ethynylaniline Hydrochloride 3-cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile 3-Iodo-4-methyl-n-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile Methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate (R)-methyl 2-isocyano-3-(tritylthio)propanoate (R)-methyl 2-formamido-3-(tritylthio)propanoate HYDROCORTISONE ACETATE EP IMPURITY E FUSIDIC ACID EP IMPURITY O / FUSIDIC ACID BP IMPURITY O / 16-DEACETYL FUSIDIC ACID SODIUM SALT Montelukast EP Impurity F | Montelukast USP Related Compound ERelated products of tetrahydrofuran
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