NEUROTENSIN (8-13)

CAS NO.：60482-95-3
Empirical Formula: C38H64N12O8
Molecular Weight: 816.99
MDL number: MFCD00076686
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is NEUROTENSIN (8-13)?

Biological Activity

Neurotensin (8-13) is the active fragment of neurotensin, Neurotensin (8-13) reduces cell surface NT1 receptor (NTR1) density.

in vitro

Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT ) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.

Properties of NEUROTENSIN (8-13)

Density	1.40±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
form	Solid
pka	3.41±0.10(Predicted)
color	White to off-white
Water Solubility	Water: 50 mg/mL (61.20 mM)

Safety information for NEUROTENSIN (8-13)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.