H-Lys(Boc)-OH
Synonym(s):Nε-Boc-L -lysine
- CAS NO.：2418-95-3
- Empirical Formula: C11H22N2O4
- Molecular Weight: 246.3
- MDL number: MFCD00037221
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-10-24 15:49:22
What is H-Lys(Boc)-OH?
Chemical properties
white crystalline powder
The Uses of H-Lys(Boc)-OH
It is used as therapy to treat recurrent herpes simplex infections.
General Description
H-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].
References
[1] Chen H , et al. Surfaces having dual fibrinolytic and protein resistant properties by immobilization of lysine on polyurethane through a PEG spacer. Journal of Biomedical Materials Research Part A, 2008; 90A: 940-946.
Properties of H-Lys(Boc)-OH
| Melting point: | 250 °C (dec.)(lit.) |
| Boiling point: | 389.3°C (rough estimate) |
| alpha | 17 º (c=1% in acetic acid) |
| Density | 1.1313 (rough estimate) |
| refractive index | 18 ° (C=1, AcOH) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| form | powder to crystal |
| pka | 2.53±0.24(Predicted) |
| color | White to Almost white |
| optical activity | [α]20/D +18°, c = 1 in acetic acid |
| Water Solubility | Slightly soluble in water. |
| BRN | 2417626 |
| CAS DataBase Reference | 2418-95-3(CAS DataBase Reference) |
Safety information for H-Lys(Boc)-OH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for H-Lys(Boc)-OH
| InChIKey | VVQIIIAZJXTLRE-QMMMGPOBSA-N |
Abamectin manufacturer
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product: H-Lys(Boc)-OH 98%
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