H-Lys(Boc)-OH

Synonym(s):N_ε-Boc-L-lysine

CAS NO.：2418-95-3
Empirical Formula: C11H22N2O4
Molecular Weight: 246.3
MDL number: MFCD00037221
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-24 15:49:22

What is H-Lys(Boc)-OH?

Chemical properties

white crystalline powder

The Uses of H-Lys(Boc)-OH

It is used as therapy to treat recurrent herpes simplex infections.

General Description

H-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].

References

[1] Chen H , et al. Surfaces having dual fibrinolytic and protein resistant properties by immobilization of lysine on polyurethane through a PEG spacer. Journal of Biomedical Materials Research Part A, 2008; 90A: 940-946.

Properties of H-Lys(Boc)-OH

Melting point:	250 °C (dec.)(lit.)
Boiling point:	389.3°C (rough estimate)
alpha	17 º (c=1% in acetic acid)
Density	1.1313 (rough estimate)
refractive index	18 ° (C=1, AcOH)
storage temp.	2-8°C
solubility	Soluble in DMSO
form	powder to crystal
pka	2.53±0.24(Predicted)
color	White to Almost white
optical activity	[α]20/D +18°, c = 1 in acetic acid
Water Solubility	Slightly soluble in water.
BRN	2417626
CAS DataBase Reference	2418-95-3(CAS DataBase Reference)

Safety information for H-Lys(Boc)-OH

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.