N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
Synonym(s):Nω-Hydroxy-nor-L-arginine, Diacetate Salt - CAS 189302-40-7 - Calbiochem;nor-NOHA, 2CH₃CO₂H, L-2-Amino-(4-(2ʹ-hydroxyguanidino)butyric Acid, 2CH₃CO₂H
- CAS NO.：189302-40-7
- Empirical Formula: C5H12N4O3
- Molecular Weight: 176.17
- MDL number: MFCD01318777
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT?
Chemical properties
Off-white powder
Definition
ChEBI: Nomega-hydroxy-nor-l-arginine is a L-alpha-amino acid.
General Description
A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 μM) and mouse macrophages (IC50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
Biochem/physiol Actions
Primary Targetarginase from rat liver
Properties of N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
| storage temp. | Store at 0°C |
| form | White to slightly yellowish powder. |
Safety information for N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
Computed Descriptors for N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT
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