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HomeProduct name listN-Methylacetoacetamide

N-Methylacetoacetamide

  • CAS NO.:20306-75-6
  • Empirical Formula: C5H9NO2
  • Molecular Weight: 115.13
  • MDL number: MFCD00044026
  • EINECS: 243-723-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-24 19:47:01
N-Methylacetoacetamide Structural

What is N-Methylacetoacetamide?

Chemical properties

Colourless to yellowish clear liquid

The Uses of N-Methylacetoacetamide

N-Methylacetoacetamide (min. 70% in water) (MMAA) is used as intermediate for the manufacture of insecticides, e.g. monocrotophos Product Data Sheet

The Uses of N-Methylacetoacetamide

N-Methylacetoacetamide is a starting material in the synthesis of 1-Carbamoyl-2-oxopropyl acetate with the aid (diacetoxyiodo)benzene (DIB) as the oxidant. Also, it is a reagent used in the synthesis of 10H-Phenothiazines, which possesses for their biological activity against the regulatory enzymes involved in inflammatory diseases.

Definition

ChEBI: N-Methylacetoacetamide is a fatty amide.

Properties of N-Methylacetoacetamide

Melting point: -3 °C
Boiling point: 106°C
Density  1.069
refractive index  1.4325-1.4345
Flash point: 105 °C
storage temp.  2-8°C
solubility  hydrolysis
form  clear liquid
pka 12.79±0.46(Predicted)
color  Light yellow to Yellow to Orange
Water Solubility  hydrolysis
CAS DataBase Reference 20306-75-6(CAS DataBase Reference)
EPA Substance Registry System Butanamide, N-methyl-3-oxo- (20306-75-6)

Safety information for N-Methylacetoacetamide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P233:Keep container tightly closed.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304:IF INHALED:
P312:Call a POISON CENTER or doctor/physician if you feel unwell.
P321:Specific treatment (see … on this label).
P340:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362:Take off contaminated clothing and wash before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.
P403:Store in a well-ventilated place.
P405:Store locked up.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.
P501:Dispose of contents/container to..…

Computed Descriptors for N-Methylacetoacetamide

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