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HomeProduct name listN-(HYDROXYMETHYL)ACETAMIDE

N-(HYDROXYMETHYL)ACETAMIDE

  • CAS NO.:625-51-4
  • Empirical Formula: C3H7NO2
  • Molecular Weight: 89.09
  • MDL number: MFCD00014417
  • EINECS: 210-897-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-19 15:36:20
N-(HYDROXYMETHYL)ACETAMIDE Structural

What is N-(HYDROXYMETHYL)ACETAMIDE?

Chemical properties

white to light yellow crystalline powder

The Uses of N-(HYDROXYMETHYL)ACETAMIDE

N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.

The Uses of N-(HYDROXYMETHYL)ACETAMIDE

Antiseptic, disinfectant especially for surgical instruments.

Purification Methods

Recrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.]

Properties of N-(HYDROXYMETHYL)ACETAMIDE

Melting point: 48-52 °C
Boiling point: 165.17°C (rough estimate)
Density  1.14
refractive index  1.4368 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Sparingly, Sonicated), DMSO (Slightly), Methanol (Slightly)
pka 13.28±0.10(Predicted)
form  Crystalline
color  White to Off-White Low-Melting
Water Solubility  Soluble
Sensitive  Hygroscopic
Merck  14,4242
BRN  506226
CAS DataBase Reference 625-51-4(CAS DataBase Reference)

Safety information for N-(HYDROXYMETHYL)ACETAMIDE

Computed Descriptors for N-(HYDROXYMETHYL)ACETAMIDE

InChIKey HWJHZLJIIWOTGZ-UHFFFAOYSA-N

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