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HomeProduct name listN-FORMYL-MET-LEU-PHE

N-FORMYL-MET-LEU-PHE

Synonym(s):Chemotactic peptide;fMLF;fMLP (misnomer but widely used);N-Formyl-L-methionyl-L-leucyl-L-phenylalanine

  • CAS NO.:5979-11-3
  • Empirical Formula: C50H73N15O11.3C2H4O2
  • Molecular Weight: 1240.38
  • MDL number: MFCD00036780
  • EINECS: 227-781-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
N-FORMYL-MET-LEU-PHE Structural

What is N-FORMYL-MET-LEU-PHE?

The Uses of N-FORMYL-MET-LEU-PHE

N-Formyl-Met-Leu-Phe is an inducer of superoxide release and agonist for FPR1.

What are the applications of Application

Bradykinin triacetate is a pro-inflammatory polypeptide

Purification Methods

Purify Bradykinin by ion-exchange chromatography on CMC (O-carboxymethyl cellulose) and partition chromatography on Sephadex G-25. The purity is checked by paper chromatography using BuOH/AcOH/H2O (4:1:5) as eluent. [Park et al. Can J Biochem 56 92 1978, ORD and CD: Bodanszky et al. Experientia 26 948 1970, activity: Regoli & Barabé Pharmacol Rev 32 1 1980, Beilstein 22 III/IV 91.]

Properties of N-FORMYL-MET-LEU-PHE

Melting point: 150-160℃
alpha  -84.1 (D/23℃) (c=1.1, H2O)-78.4 (D/25℃) (c=1.4, 1N AcOH)
storage temp.  2-8°C
solubility  DMF: 50 mg/mL, clear, colorless
form  powder
color  white
CAS DataBase Reference 5979-11-3(CAS DataBase Reference)

Safety information for N-FORMYL-MET-LEU-PHE

Computed Descriptors for N-FORMYL-MET-LEU-PHE

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