N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

CAS NO.：110025-28-0
Empirical Formula: C25H27NO2
Molecular Weight: 373.49
MDL number: MFCD09840374
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)?

Chemical properties

Brown Foam

The Uses of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca

The Uses of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

What are the applications of Application

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) is novel active metabolite of the anti-cancer drug Tamoxifen

storage

Store at +4°C

Properties of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

Melting point:	63-72°C
Boiling point:	519.3±50.0 °C(Predicted)
Density	1.099±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform, Dichloromethane, DMSO, Methanol
form	Solid
pka	9.38±0.15(Predicted)
color	Light Brown to Light Purple

Safety information for N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…