3-Cyclohexylaminopropanesulfonic Acid
Synonym(s):Caps;3-(Cyclohexylamino)-1-propanesulfonic acid;Accessories;Pipettes;Piston-operated pipettes
- CAS NO.:1135-40-6
- Empirical Formula: C9H19NO3S
- Molecular Weight: 221.32
- MDL number: MFCD00003837
- EINECS: 214-492-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-28 13:39:29
![3-Cyclohexylaminopropanesulfonic Acid Structural](https://img.chemicalbook.in/CAS/GIF/1135-40-6.gif)
What is 3-Cyclohexylaminopropanesulfonic Acid?
Chemical properties
White/clear crystalline powder
The Uses of 3-Cyclohexylaminopropanesulfonic Acid
CAPS (N-cyclohexyl-3-aminopropanesulfonic acid) buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718,?sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good?s buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects.
The Uses of 3-Cyclohexylaminopropanesulfonic Acid
3-Cyclohexylaminopropanesulfonic Acid buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good's buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects. It is a biological buffer.
What are the applications of Application
CAPS is used to formulate CAPS buffer, a zwitterionic buffer useful in the range of pH 7.9-11.1
definition
ChEBI: Cyclohexylaminopropanesulfonic acid is an amine.
Flammability and Explosibility
Not classified
Properties of 3-Cyclohexylaminopropanesulfonic Acid
Melting point: | >300 °C(lit.) |
Density | 1.1809 (rough estimate) |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.5250 (estimate) |
Flash point: | >110℃ |
storage temp. | room temp |
solubility | H2O: 0.5 M at 20 °C, clear |
form | Powder/Solid |
color | White |
PH | 3.0-7.0 (20℃, 0.5M in H2O) |
pka | 10.4(at 25℃) |
Odor | Odorless |
PH Range | 3 - 7 |
Water Solubility | 9 g/100 mL (20 ºC) |
λmax | λ: 260 nm Amax: ≤0.04 λ: 280 nm Amax: ≤0.04 |
Merck | 14,1767 |
BRN | 2835588 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 1135-40-6(CAS DataBase Reference) |
EPA Substance Registry System | 1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6) |
Safety information for 3-Cyclohexylaminopropanesulfonic Acid
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 3-Cyclohexylaminopropanesulfonic Acid
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