N-Carbethoxy-4-piperidone

Synonym(s):1-Carbethoxy-4-piperidone;1-Ethoxycarbonyl-4-piperidone

CAS NO.：29976-53-2
Empirical Formula: C8H13NO3
Molecular Weight: 171.19
MDL number: MFCD00006188
EINECS: 249-984-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-12 11:13:47

What is N-Carbethoxy-4-piperidone ?

Chemical properties

clear colorless to pale yellow colored liquid

The Uses of N-Carbethoxy-4-piperidone

N-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. It is also an impurity of Loratadine (L469575).

The Uses of N-Carbethoxy-4-piperidone

Ethyl 4-oxo-1-piperidinecarboxylate (1-carbethoxy-4-piperidone) was used to prepare tertiary alcohols.

Properties of N-Carbethoxy-4-piperidone

Boiling point:	95-98 °C (1 mmHg)
Density	1.135 g/mL at 25 °C (lit.)
vapor pressure	0.2-0.37Pa at 20-25℃
refractive index	n20/D 1.475(lit.)
Flash point:	190 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
pka	-1.59±0.20(Predicted)
color	Clear colorless to pale yellow
PH	4.6 (H2O, 20℃)(saturated solution)
Water Solubility	slightly soluble
BRN	640967
CAS DataBase Reference	29976-53-2(CAS DataBase Reference)

Safety information for N-Carbethoxy-4-piperidone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention.