N-BENZYLCINCHONINIUM CHLORIDE
Synonym(s):9-Hydroxy-1-(phenylmethyl)cinchonanium chloride;BCNC
- CAS NO.:69221-14-3
- Empirical Formula: C26H29ClN2O
- Molecular Weight: 420.97
- MDL number: MFCD00082423
- EINECS: 273-915-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:37
What is N-BENZYLCINCHONINIUM CHLORIDE?
Chemical properties
Solid
The Uses of N-BENZYLCINCHONINIUM CHLORIDE
Phase-transfer catalyst involved in:
- Enantioselective alkylation of malonic diester with alkyl halides
- Hydrolysis of enol esters
- Asymmetric 6π electrocyclization for synthesis of functionalized indolines
- Asymmetric Michael addition
- Alkylation of monosubstituted indolinones with alkylhalides
- Asymmetric destruction and kinetic resolution of 1-benzylated Reissert compounds
Purification Methods
Recrystallise the chloride from isoPrOH, toluene or small volumes of H2O. It is a good chiral phase transfer catalyst [Julia et al. J Chem Soc, Perkin Trans 1 574 1981, Hughes et al. J Am Chem Soc 106 446 1984, Hughes et al. J Org Chem 52 4745 1987].
Properties of N-BENZYLCINCHONINIUM CHLORIDE
Melting point: | 256 °C (dec.)(lit.) |
refractive index | 168.5 ° (C=0.4, MeOH:H2O=1:5) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | slightly sol. in Methanol |
form | powder to crystaline |
color | White to Almost white |
optical activity | [α]20/D +169°, c = 0.4 in H2O |
BRN | 5232950 |
CAS DataBase Reference | 69221-14-3(CAS DataBase Reference) |
Safety information for N-BENZYLCINCHONINIUM CHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for N-BENZYLCINCHONINIUM CHLORIDE
New Products
Tubulysin D Tubulysin E Tubulysin G Diethyl Aluminium Cyanide (1.0 M in Toluene) tetrahydro-4-methyl-2H-pyran 4,4-DIFLUOROPIPERIDINE 2,2-Difluoropropylamine hydrochloride 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 3-Aminocyclobutanone hydrochloride 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Calcium Sodium Phosphosilicate IH (R)-Methanesulfonic acid 3-(3-fluoro-4- morpholin-4-yl- phenyl)-2-oxo- oxazolidin-5-ylmethyl 4-(2-fluoro-4- nitrophenyl) thiomorpholine Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
N-Benzyl-N-methylpiperidinium chloride
(R)(-)-2-BENZYLAMINO-1-BUTANOL
N-BENZYLCINCHONINIUM CHLORIDE
N-BENZYLQUINIDINIUM CHLORIDE
2-HYDROXY-4-PYRIDYLETHYLAMINE
6-BENZYLAMINO-1-HEXANOL
Methyltripropyl ammonium chloride
Cinchonine
You may like
-
N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst] CAS 69221-14-3View Details
69221-14-3 -
N-Benzylcinchoninium chloride CAS 69221-14-3View Details
69221-14-3 -
Fuel shell 98%View Details
-
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Hydrogen Gas 98%View Details
-
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.