N-BENZYLCINCHONINIUM CHLORIDE
Synonym(s):9-Hydroxy-1-(phenylmethyl)cinchonanium chloride;BCNC
- CAS NO.：69221-14-3
- Empirical Formula: C26H29ClN2O
- Molecular Weight: 420.97
- MDL number: MFCD00082423
- EINECS: 273-915-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:37
What is N-BENZYLCINCHONINIUM CHLORIDE?
Chemical properties
Solid
The Uses of N-BENZYLCINCHONINIUM CHLORIDE
Phase-transfer catalyst involved in:
- Enantioselective alkylation of malonic diester with alkyl halides
- Hydrolysis of enol esters
- Asymmetric 6π electrocyclization for synthesis of functionalized indolines
- Asymmetric Michael addition
- Alkylation of monosubstituted indolinones with alkylhalides
- Asymmetric destruction and kinetic resolution of 1-benzylated Reissert compounds
Purification Methods
Recrystallise the chloride from isoPrOH, toluene or small volumes of H2O. It is a good chiral phase transfer catalyst [Julia et al. J Chem Soc, Perkin Trans 1 574 1981, Hughes et al. J Am Chem Soc 106 446 1984, Hughes et al. J Org Chem 52 4745 1987].
Properties of N-BENZYLCINCHONINIUM CHLORIDE
| Melting point: | 256 °C (dec.)(lit.) |
| refractive index | 168.5 ° (C=0.4, MeOH:H2O=1:5) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | slightly sol. in Methanol |
| form | powder to crystaline |
| color | White to Almost white |
| optical activity | [α]20/D +169°, c = 0.4 in H2O |
| BRN | 5232950 |
| CAS DataBase Reference | 69221-14-3(CAS DataBase Reference) |
Safety information for N-BENZYLCINCHONINIUM CHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for N-BENZYLCINCHONINIUM CHLORIDE
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
![N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst] CAS 69221-14-3](https://img.chemicalbook.in//Content/image/CP5.jpg)
N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst] CAS 69221-14-3View Details
69221-14-3 -
N-Benzylcinchoninium chloride CAS 69221-14-3View Details
69221-14-3 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.