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HomeProduct name listN-Benzoyl-2'-deoxy-adenosine

N-Benzoyl-2'-deoxy-adenosine

  • CAS NO.:4546-72-9
  • Empirical Formula: C17H17N5O4
  • Molecular Weight: 355.35
  • MDL number: MFCD00009628
  • EINECS: 224-903-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
N-Benzoyl-2'-deoxy-adenosine Structural

What is N-Benzoyl-2'-deoxy-adenosine?

Description

N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

The Uses of N-Benzoyl-2'-deoxy-adenosine

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.

Properties of N-Benzoyl-2'-deoxy-adenosine

Melting point: 120-122C
Density  1.61±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form  A crystalline solid
pka 7.87±0.43(Predicted)
Water Solubility  Soluble in water (slightly), and methanol (20 mg/ml).
CAS DataBase Reference 4546-72-9(CAS DataBase Reference)

Safety information for N-Benzoyl-2'-deoxy-adenosine

Computed Descriptors for N-Benzoyl-2'-deoxy-adenosine

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