6-Chloropurine riboside
Synonym(s):6-Chloropurine-9-β-D -ribofuranoside
- CAS NO.：5399-87-1
- Empirical Formula: C10H11ClN4O4
- Molecular Weight: 286.67
- MDL number: MFCD00005738
- EINECS: 226-438-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is 6-Chloropurine riboside?
Chemical properties
Colourless Crystalline Powder
The Uses of 6-Chloropurine riboside
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
The Uses of 6-Chloropurine riboside
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
The Uses of 6-Chloropurine riboside
A substrate for adenosine deaminase
Properties of 6-Chloropurine riboside
| Melting point: | 158-162 °C (dec.) (lit.) |
| Boiling point: | 614.8±65.0 °C(Predicted) |
| Density | 2.03±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO (Sparingly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated, |
| form | Powder |
| pka | 13.06±0.70(Predicted) |
| color | White to slightly yellow |
| Water Solubility | Soluble in water. (10.6 mg/mL) |
| BRN | 40573 |
| CAS DataBase Reference | 5399-87-1(CAS DataBase Reference) |
Safety information for 6-Chloropurine riboside
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 6-Chloropurine riboside
| InChIKey | XHRJGHCQQPETRH-HMEJCUHCSA-N |
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
6-Chloropurine Riboside CAS 5399-87-1View Details
5399-87-1 -
6-Chloropurine riboside CAS 5399-87-1View Details
5399-87-1 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1