N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

CAS NO.：2098488-36-7
Empirical Formula: C19H20N6O6
Molecular Weight: 428.3987
MDL number: MFCD31560486
Update Date: 2024-07-02 08:55:00

What is N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?

Description

UUN 88367, also known as Azido-Thalidomide is a clickable Thalidomide derivative, used as a building block for cereblon. Azido-Thalidomide targets PROTACs by hijacking cereblon as the E3 ubiquitin ligase component. This product has no formal name at the moment.

storage

Store at -20°C

Properties of N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

solubility	DMF: 12 mg/ml; DMSO: 12 mg/ml; DMSO:PBS (pH 7.2)(1:8): 0.11 mg/ml
form	A crystalline solid
color	White to off-white

Safety information for N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

Computed Descriptors for N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

New Products

6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin H Tubulysin A Tubulysin G Diethyl Aluminium Cyanide (1.0 M in Toluene) 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell Calcium Sodium Phosphosilicate IH 4,8-dibromo-5H-[1,2,3]triazolo[4',5':4,5]benzo[1,2-c][1,2,5]thiadiazole Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester 1-(4-Fluorophenyl)piperidin-2-one 3,3,6,6-Tetramethylcyclohexane-1,2-dione 4-(Azidomethyl)-3-chloropyridine 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 4,6-difluoro-1H-indole 6-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one 4-bromopyrimidin-2-amine

Related products of tetrahydrofuran

E3 Ligase Ligand-Linker Conjugates 24 (TFA)

E3 Ligase Ligand-Linker Conjugates 20

Thalidomide-linker 13

Thalidomide-linker 14

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

Thalidomide-O-amido-PEG4-azide

Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Thalidomide-O-amido-C8-NH2 hydrochloride