N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
- CAS NO.：474-74-8
- Empirical Formula: C26H43NO4
- Molecular Weight: 433.63
- MDL number: MFCD00067140
- EINECS: 207-494-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
![N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine Structural](https://img.chemicalbook.in/CAS/GIF/474-74-8.gif)
What is N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine?
Description
Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid . It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid . Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of PEG-obestatin(Cys10, Cys13), a modified peptide hormone, in lean or diet-induced obese mice. Serum glycolithocholic acid levels increase with age in children.
The Uses of N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
A metabolite in human hepatic bile.
The Uses of N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.
What are the applications of Application
Lithocholylglycine is a lithocholic acid analog that inhibits sialyltransferase
Definition
ChEBI: The glycine conjugate of lithocholic acid.
Properties of N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
| Melting point: | 212-214 °C |
| Boiling point: | 546.95°C (rough estimate) |
| Density | 1.0738 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly, Heated), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 3.58±0.10(Predicted) |
| color | White to Off-White |
Safety information for N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
Computed Descriptors for N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine
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