N-(3-Trifluoromethylphenyl)piperazine
- CAS NO.：15532-75-9
- Empirical Formula: C11H13F3N2
- Molecular Weight: 230.23
- MDL number: MFCD00005959
- EINECS: 239-574-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:32
What is N-(3-Trifluoromethylphenyl)piperazine?
Chemical properties
clear colourless to yellow slightly viscous liquid
The Uses of N-(3-Trifluoromethylphenyl)piperazine
1-[3-(Trifluoromethyl)phenyl]piperazine is used in preparation of (Piperazinylethyl)cyclohexanamide derivatives and used as treatment or prevention of D3 and/or 5HT-2 receptor diseases.
Definition
ChEBI: A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.
Synthesis Reference(s)
Tetrahedron Letters, 37, p. 319, 1996 DOI: 10.1016/0040-4039(95)02162-0
Properties of N-(3-Trifluoromethylphenyl)piperazine
| Boiling point: | 100-102°C 0,1mm |
| Density | 1.226 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | -20°C |
| form | neat |
| pka | 8.88±0.10(Predicted) |
| Sensitive | Air Sensitive |
| BRN | 614217 |
| CAS DataBase Reference | 15532-75-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Piperazine, 1-[3-(trifluoromethyl)phenyl]-(15532-75-9) |
Safety information for N-(3-Trifluoromethylphenyl)piperazine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for N-(3-Trifluoromethylphenyl)piperazine
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
![2-METHYL-2-(4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)PROPANENITRILE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1110418.gif)
![(2,4-DIPHENYL-5-PYRIMIDINYL)(4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)METHANONE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB6699132.gif)
![N,N-DIMETHYL-4-(TRIFLUOROMETHYL)-6-(4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)-2-PYRIMIDINAMINE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB9703087.gif)
![2,4-BIS(TRIFLUOROMETHYL)-7-(4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)[1,8]NAPHTHYRIDINE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB5668902.gif)
![2-(4-[3-(TRIFLUOROMETHYL)PHENYL]PIPERAZINO)QUINOXALINE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB0493266.gif)
You may like
-
N-(-(3-Trifluoromethyl)phenyl)piperazine 98% (GC) CAS 15532-75-9View Details
15532-75-9 -
Dechloro DesloratadineView Details -
Dehydro DesloratadineView Details -
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details -
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.