N-(2-FUROYL)GLYCINE

CAS NO.：5657-19-2
Empirical Formula: C7H7NO4
Molecular Weight: 169.13
MDL number: MFCD00030606
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is N-(2-FUROYL)GLYCINE?

The Uses of N-(2-FUROYL)GLYCINE

2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.

Definition

ChEBI: N-(2-furoyl)glycine is a glycine derivative that is the carboxamide obtained by the formal condensation of the amino group of glycine with 2-furoic acid. It has a role as a human metabolite. It is a N-acylglycine and a member of furans. It is functionally related to a 2-furoic acid. It is a conjugate acid of a N-(2-furoyl)glycinate.

Properties of N-(2-FUROYL)GLYCINE

Melting point:	163-165 °C(lit.)
Boiling point:	466.0±25.0 °C(Predicted)
Density	1.367±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	3.66±0.10(Predicted)
color	White to Off-White
Water Solubility	>21.55 mg/mL in Water with ultrasonic;
Stability:	Hygroscopic

Safety information for N-(2-FUROYL)GLYCINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.