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HomeProduct name listN-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Structural

What is N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid?

The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

Treatment of Alzheimer’s disease.

The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.

What are the applications of Application

Lazabemide hydrochloride is a selective and reversible monoamine oxidase B inhibitor

Definition

ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.

brand name

Tempium (Hoffmann-LaRoche).

Biological Activity

Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).

storage

Desiccate at RT

Properties of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

Melting point: 193-195°
storage temp.  Desiccate at RT
solubility  Soluble to 100 mM in water and to 100 mM in DMSO
form  Powder
pka 8.9(at 25℃)

Safety information for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

Computed Descriptors for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid

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