N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- CAS NO.:103878-83-7
- Empirical Formula: C8H10ClN3O.HCl
- Molecular Weight: 0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 21:40:10
What is N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid?
The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Treatment of Alzheimer’s disease.
The Uses of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.
What are the applications of Application
Lazabemide hydrochloride is a selective and reversible monoamine oxidase B inhibitor
Definition
ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.
brand name
Tempium (Hoffmann-LaRoche).
Biological Activity
Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).
storage
Desiccate at RT
Properties of N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Melting point: | 193-195° |
storage temp. | Desiccate at RT |
solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
form | Powder |
pka | 8.9(at 25℃) |
Safety information for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
Computed Descriptors for N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Cysteamine hydrochloride
Methylamine hydrochloride
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE
5-Chloropyridine-2-carboxamide
LAZABEMIDE
5-CHLORO-2-FORMYLPYRIDINE
METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE
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