MRS 1706

Synonym(s):8-[4-[((4-Acetylphenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine;MRS 1706;MRS1706;N-(4-Acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide;N-(4-Acetylphenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide

CAS NO.：264622-53-9
Empirical Formula: C27H29N5O5
Molecular Weight: 503.55
MDL number: MFCD28160689
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is MRS 1706?

Description

MRS1706 is a selective adenosine A_2B receptor inverse agonist with K_i values of 1.39, 157, 112, and 230 nM for human A_2B, A₁, A_2A, and A₃ receptors, respectively.

The Uses of MRS 1706

MRS 1706 is a selective and potent Adenosine A2B-R inverse agonist Ki (binding affinity) values of 1.39, 157, 112, and 230 nM for human A2B, A1, A2A, and A3 receptors, respectively.

What are the applications of Application

MRS 1706 is a selective and potent Adenosine A2B-R inverse agonist

Biological Activity

Potent and selective adenosine A 2B receptor inverse agonist (K i values are 1.39, 157, 112 and 230 nM for human A 2B , A 1 , A 2A and A 3 receptors respectively).

Properties of MRS 1706

Density	1.293±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO : 6.4 mg/mL (12.71 mM; Need ultrasonic and warming)H2O : < 0.1 mg/mL (insoluble)
form	Powder
pka	8.25±0.70(Predicted)
color	Off-white to yellow