m-PEG8-NHS ester
- CAS NO.：756525-90-3
- Empirical Formula: C22H39NO12
- Molecular Weight: 509.54
- MDL number: MFCD13184969
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-27 13:09:27
What is m-PEG8-NHS ester ?
Description
m-PEG8-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Properties of m-PEG8-NHS ester
| storage temp. | -20°C |
| solubility | Soluble in DMSO, DCM, DMF |
| form | solid or viscous liquid |
| color | Colorless to Yellow |
| InChI | InChI=1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3 |
| CAS DataBase Reference | 756525-90-3 |
Safety information for m-PEG8-NHS ester
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for m-PEG8-NHS ester
| InChIKey | IBZNTYBFTKFSMU-UHFFFAOYSA-N |
| SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOC |
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