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HomeProduct name listMPEG11-CH2CH2COONHS

MPEG11-CH2CH2COONHS

  • CAS NO.:2207596-93-6
  • Empirical Formula: C30H55NO16
  • Molecular Weight: 685.75
  • MDL number: MFCD13184970
  • Update Date: 2024-07-02 08:54:57
MPEG11-CH2CH2COONHS Structural

What is MPEG11-CH2CH2COONHS?

Biological Activity

m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Properties of MPEG11-CH2CH2COONHS

Boiling point: 684.3±65.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
form  Liquid
color  Colorless to light yellow

Safety information for MPEG11-CH2CH2COONHS

Computed Descriptors for MPEG11-CH2CH2COONHS

InChIKey ZMXRHHJWXLKMTL-UHFFFAOYSA-N
SMILES C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

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