MPEG11-CH2CH2COONHS
- CAS NO.：2207596-93-6
- Empirical Formula: C30H55NO16
- Molecular Weight: 685.75
- MDL number: MFCD13184970
- Update Date: 2024-07-02 08:54:57
What is MPEG11-CH2CH2COONHS?
Biological Activity
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of MPEG11-CH2CH2COONHS
| Boiling point: | 684.3±65.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for MPEG11-CH2CH2COONHS
Computed Descriptors for MPEG11-CH2CH2COONHS
| InChIKey | ZMXRHHJWXLKMTL-UHFFFAOYSA-N |
| SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
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