Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listMOLLUGIN

MOLLUGIN

Synonym(s):6-Hydroxy-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5-carboxylic acid methyl ester;Rubimaillin

  • CAS NO.:55481-88-4
  • Empirical Formula: C17H16O4
  • Molecular Weight: 284.31
  • MDL number: MFCD02752331
  • EINECS: 683-209-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 15:53:33
MOLLUGIN Structural

What is MOLLUGIN?

The Uses of MOLLUGIN

Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.

Definition

ChEBI: Rubimaillin is a benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. It has a role as a plant metabolite, an acyl-CoA:cholesterol acyltransferase 2 inhibitor, a NF-kappaB inhibitor, an antineoplastic agent, an apoptosis inducer, a neuroprotective agent and an anti-inflammatory agent. It is a benzochromene, a methyl ester and a member of phenols.

Properties of MOLLUGIN

Melting point: 132~134℃
Boiling point: 453.2±45.0 °C(Predicted)
Density  1.239±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly)
form  Solid
pka 8.40±0.40(Predicted)
color  Yellow to Green

Safety information for MOLLUGIN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for MOLLUGIN

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.