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HomeProduct name listMOLINDONE HYDROCHLORIDE (500 MG)

MOLINDONE HYDROCHLORIDE (500 MG)

MOLINDONE HYDROCHLORIDE (500 MG) Structural

What is MOLINDONE HYDROCHLORIDE (500 MG)?

Chemical properties

Light Tan Solid

Originator

Moban,Endo,US,1974

The Uses of MOLINDONE HYDROCHLORIDE (500 MG)

D2 Dopamine receptor antagonist. MAO inhibitor. Antipsychotic.

The Uses of MOLINDONE HYDROCHLORIDE (500 MG)

Antipsychotic;Dopamine receptor antagonist

What are the applications of Application

Molindone Hydrochloride is a D2DR inhibitor and a MAO inhibitor

Definition

ChEBI: Molindone hydrochloride is a member of indoles.

Manufacturing Process

Diethyl ketone may be reacted with methyl nitrite and that product in turn reacted with cyclohexan-1,3-dione to give 3-ethyl-4,5,6,7-tetrahydro-2- methyl-4-oxoindole.
3-ethyl-4,5,6,7-tetrahydro-2-methyl-4-oxoindole 14.1 g (0.08 mol), 14.8 g morpholine hydrochloride (0.12 mol), and 3.6 g paraformaldehyde (0.12 mol) were refluxed in 200 ml ethanol for 40 hours. The solution was evaporated to dryness in vacuo on a steam bath and the residue digested with a mixture of 150 ml water and 10 ml 2N HCl. An insoluble residue of unreacted starting material was filtered off. To the acid solution, ammonia water was added dropwise with stirring and the amine crystallized out. It was purified by dissolving in 1N HCl and addition of ammonia, then by 2 crystallizations from benzene followed by 2 crystallizations from isopropanol, to yield 3-ethyl- 4,5,6,7-tetrahydro-2-methyl-4-oxoindole, melting point 180°C to 181°C.

brand name

Moban (Endo).

Therapeutic Function

Antipsychotic

Properties of MOLINDONE HYDROCHLORIDE (500 MG)

Melting point: 211-213°C
storage temp.  Inert atmosphere,Room Temperature
solubility  H2O: soluble19mg/mL
form  solid
color  off-white
Merck  14,6233

Safety information for MOLINDONE HYDROCHLORIDE (500 MG)

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral

Computed Descriptors for MOLINDONE HYDROCHLORIDE (500 MG)

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