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HomeProduct name listMILBEMECTIN A4

MILBEMECTIN A4

MILBEMECTIN A4 Structural

What is MILBEMECTIN A4?

Description

Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.

The Uses of MILBEMECTIN A4

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

The Uses of MILBEMECTIN A4

Acaricide.

The Uses of MILBEMECTIN A4

Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3).

What are the applications of Application

Milbemycin A4 is an antibiotic with acaricidal activity

Definition

ChEBI: Milbemycin A4 is a milbemycin.

Properties of MILBEMECTIN A4

Melting point: 212-215°
Boiling point: 732.9±60.0 °C(Predicted)
alpha  D20 +106° (c = 0.25 in acetone)
Density  1.20±0.1 g/cm3(Predicted)
storage temp.  0-6°C
solubility  DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form  A solid
pka 12.46±0.70(Predicted)
color  White to off-white
EPA Substance Registry System Milbemycin A4 (51596-11-3)

Safety information for MILBEMECTIN A4

Computed Descriptors for MILBEMECTIN A4

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