MILBEMECTIN A3

Description

Milbemycin A₃ is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A₃ is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A₃ and milbemycin A₄ against adult spider mites, spider mite eggs, and C. elegans are reported at IC₅₀ values of 5.3, 41.1, and 9.5 μg/ml.

The Uses of MILBEMECTIN A3

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is a major member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

The Uses of MILBEMECTIN A3

Milbemycin A3 is widely used as a pesticides in agriculture. Milbemycin A3 (Milbemycin EP Impurity B) is an antibiotic with acaricidal activity.

What are the applications of Application

Milbemycin A3 is an antibiotic with acaricidal activity

Definition

ChEBI: Milbemycin A3 is a milbemycin.