Methyl nitroacetate
- CAS NO.：2483-57-0
- Empirical Formula: C3H5NO4
- Molecular Weight: 119.08
- MDL number: MFCD00075480
- EINECS: 219-622-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-15 16:23:59
What is Methyl nitroacetate?
Chemical properties
clear yellow liquid
The Uses of Methyl nitroacetate
Methyl nitroacetate is used in the synthesis of aromatic and heteroaromatic linear (E)-alfa-nitro-arylpentenoates. It is also used to prepare phenyliodonium ylide. Further, it is utilized in the highly enantioselective and diastereoselective copper(I)-catalyzed cyclopropanation of alkenes. In addition to this, it is employed in the production of methyl (Z)-2-nitro-3-(4-nitrophenyl)-2-propenoate through reaction with 4-nitrobenzylideneaniline.
Synthesis Reference(s)
The Journal of Organic Chemistry, 25, p. 266, 1960 DOI: 10.1021/jo01072a606
Properties of Methyl nitroacetate
| Boiling point: | 195-198 °C (lit.) |
| Density | 1.294 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 221 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Miscible with ethanol, ether and most organic solvents. |
| form | clear liquid |
| pka | 5.73±0.29(Predicted) |
| color | Colorless to Light yellow |
| Sensitive | Light Sensitive |
| BRN | 1758670 |
| CAS DataBase Reference | 2483-57-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, nitro-, methyl ester(2483-57-0) |
Safety information for Methyl nitroacetate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Methyl nitroacetate
| InChIKey | ALBSWLMUHHZLLR-UHFFFAOYSA-N |
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
Methyl nitroacetate CAS 2483-57-0View Details
2483-57-0 -
Methyl Nitroacetate CAS 2483-57-0View Details
2483-57-0 -
Methyl nitroacetate 98% (GC) CAS 2483-57-0View Details
2483-57-0 -
Methyl nitroacetate CAS 2483-57-0View Details
2483-57-0 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.