Methyl isoeugenol

Description

Isoeugenyl methyl ether has a delicate, clove-carnation odor and a burning bitter taste. May be prepared by methylation of isoeugenol with methyl sulfate in alkaline solution.

Chemical properties

light yellow liquid

Chemical properties

Isoeugenol Methyl Ether occurs in small quantities in several essential oils. It is a colorless to pale yellow liquid with a mild clove odor.

Occurrence

The natural and the commercial products are a mixture of cis- and trans-isomers; originally isolated in the oil roots of Asarum arifolium Michx.; in the oil of Cymbopogon javanensis, Orthodon methylisoeugenoliferum F. (approx. 53%) and others. Reported found in orange peel oil, ginger, calamus, dried bonito and mastic gum leaf and fruit oil.

The Uses of Methyl isoeugenol

Methyl isoeugenol can be used as a natural food flavor in food industries.

The Uses of Methyl isoeugenol

Perfumery, flavoring agent.

What are the applications of Application

1,2-Dimethoxy-4-propenylbenzene is a useful and very flagrant anisole derived from eugenol

Preparation

By methylation of isoeugenol with methyl sulfate in alkaline solution

Definition

ChEBI: Isomethyleugenol is a phenylpropanoid, an olefinic compound and a dimethoxybenzene.

Toxicity evaluation

The acute oral LD₅₀ in rats was reported as 1.5 g/kg (Jenner, Hagan, Taylor, Cook & Fitzhugh, 1964) and as 2.5 g/kg (2.03-3.08 g/kg) (Keating, 1972). The ip LD₅₀ in mice was reported as 0.5 g/kg for the eis- isomer and as 0.35 g/kg for the trans- isomer (Caujolle & Meynier, 1960). The acute dermal LD₅₀ in rabbits exceeded 5 g/kg (Keating, 1972)

General Description

Methyl isoeugenol is one of the main components found in the essential oil extracted from Acorus calamus, bark of Croton malambo and rhizomes of Zingiber zerumbet, Hedychium coronarium and Etlingera cevuga.